ncRNA name | hsa-miR-34a |
ncRNA Category | miRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | RB samples and adjacent noncancerous tissues; RB cell lines HXO-RB44, SO-RB50, Y79 and WERI-RB1 |
Methods | qRT-PCR, luciferase reporter assay, Western blot, apoptosis assay |
Expression pattern | down-regulated |
Functional description | The miR‑34a/MAGE‑A/p53 axis may be conducive to enhancing the efficacies of chemotherapeutic treatments for RB. |
PubMed ID | 30387834 |
Year | 2019 |
Title | miR‑34a regulates the chemosensitivity of retinoblastoma cells via modulation of MAGE‑A/p53 signaling. |
Drug-related ncRNA | NO |
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